When a cell over-expresses NNMT, it does two costly things at once: it burns through methyl-donor capacity, and it diverts nicotinamide away from NAD+ regeneration into an inert metabolite (1-methylnicotinamide) that gets excreted
Higher Potency Ensures a therapeutic dose, unlike oral supplements that lose potency in digestion
Results can vary depending on your current levels and individual response
In addition, the negative NMO and MOG antibody tests effectively rule out neuromyelitis optica and MOG-associated disorders as alternative causes, leaving the possibility of clinically isolated syndrome (CIS) or an early demyelinating condition, such as multiple sclerosis (MS), as more probable explanations
When to Seek Help: What If I Don't Feel Better
Mood regulation: Plays a role in serotonin production, reducing depression and anxiety symptoms